Nathan Wiles pitched a season-high eight innings, allowing just two runs and Oklahoma opened its final Big 12 series of the season with a 4-2 win Thursday at Texas.
The junior right-hander scattered eight hits with eight strikeouts and no walks to improve to 8-3 on the season.
Jason Ruffcorn got three outs on just three pitches in the ninth inning to pick up his 11th save.
Brylie Ware opened the scoring for the Sooners (32-20, 10-12 Big 12) with an RBI double in the first inning.
Conor McKenna added an RBI single in the second to put OU up 2-0.