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Everyone knows what talented San Francisco 49ers running back Christian McCaffrey can achieve statistically when he is fully healthy. McCaffrey dominated fantasy football during the 2019 season, and he did it again in 2023 in his first full campaign with the 49ers, topping 2,000 yards from scrimmage and scoring 21 touchdowns, moving fantasy managers to ignore the all-or-nothing nature of relying on him.