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Final odds and predictions for Ohio State football vs Purdue

Fansided | November 8, 2025

Related Topics: The Ohio State University, Purdue Boilermakers, Ryan Day, West Lafayette

The Ohio State football team is a massive favorite over Purdue. Will they win the game?

Ohio State Buckeyes linebacker Arvell Reese (8) hits Penn State Nittany Lions wide receiver Devonte Ross (5) beside cornerback Lorenzo Styles Jr. (3) during the NCAA football game at Ohio Stadium in Columbus on Nov. 1, 2025. | Adam Cairns/Columbus Dispatch / USA TODAY NETWORK via Imagn Images

The Ohio State football team has a history of getting upset in West Lafayette by an unranked Purdue team. In 2018, it was a house of horrors for the Buckeyes.

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