Notre Dame is 4-0 straight up against Wake Forest over the last seven seasons, including a 48-37 victory last year. But the Demon Deacons are 3-1 against the spread over that span, covering as dogs three times, including last season. Who's the smart bet for Saturday afternoon's clash between the Irish and the Deacons in Winston-Salem?
College football point spread: The Fighting Irish opened as 6.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 35.0-33.4 Fighting Irish (College football picks on every game)
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