Deadline day signings Matt Gilks, Mikael Mandron, Gabriel Obertan, Jack Byrne, Josh Laurent and Alex Bruce all hope to make their Wigan debuts.
Nick Powell (hamstring), Donervon Daniels (knee), Alex Gilbey and Reece James (both ankle) are out.
Norwich are without the suspended Alex Tettey, while James Maddison (back) and Steven Naismith (hamstring) are doubts.
But Matt Jarvis, who has yet to feature this season, could be in the squad following a hamstring problem.
Match facts
- Wigan have never scored more than once in a league fixture against Norwich (seven goals in nine previous games).