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Trey Lance Likely to Make 1st Career Start for 49ers vs. Cardinals

San Francisco 49ers rookie quarterback Trey Lance may get the first start of his career Sunday against the Arizona Cardinals. ESPN's Adam Schefter reports that veteran starter Jimmy Garoppolo didn't practice on Friday, putting Lance in a good position to get the start.

Garoppolo injured his right calf in the 49ers' 28-21 loss to the Seattle Seahawks in Week 4 and hasn't practiced all week.

Lance, who has made brief appearances throughout the season, came into that game and performed well. He completed 9-of-18 passes for 157 yards and two touchdowns while adding 41 rushing yards, good for second on the team behind running back Trey Sermon.