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The MMQB Staff's Favorite Week 1 Bets Against the Spread

The NFL season is here, and that means we'll have weekly best bets from The MMQB staff here at SI Gambling. There are lots of intriguing games on the Week 1 slate, and our experts have identified their top picks to cash for this week.

Indianapolis Colts (+6.5) at Los Angeles Chargers

Such disrespect for Jacoby Brissett! Everyone is still hung up on his 2017 stat line, when he was brought to the organization five days before the season and inserted into a broken system surrounded by a Ryan Grigson-built roster. He's talented, he has a solid supporting cast, he's had a full season learning under Frank Reich (that same Frank Reich who helped get Nick Foles up to speed in time to win a Super Bowl two seasons ago) and he should be a league-average starter this season.