Indianapolis Colts center Khaled Holmes was ruled out for Monday’s showdown with the undefeated Carolina Panthers. Holmes did not return in the second half of last Sunday’s game against the New Orleans Saints after sustaining a minor neck injury.
u25a0 San Francisco waived Jarryd Hayne, who signed with the 49ers as a free agent after giving up a lucrative rugby career in Australia to take a shot at the N.F.L.