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Patrick Mahomes Knocked Out of Game by a Knee Injury

Matthew Stockman/Getty Images

The entire balance of power in the A.F.C. might have shifted Thursday night on a quarterback sneak.

Patrick Mahomes, the league’s reigning Most Valuable Player Award winner, sustained what appeared to be a serious right knee injury after surging for a first down in the second quarter of the Chiefs’ game Thursday night at Denver. After being tended to by trainers, he limped off the field and, within minutes, was ruled out for the remainder of the game.

The injury comes after Mahomes battled a left ankle injury first sustained in Week 1 and reaggravated in Sunday’s loss to the Houston Texans.