ESPN.com · Sep 13, 2025
NFL Week 2 predictions, fantasy sleepers, upset picks, bets
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Week 2 of the 2025 NFL season is here, and our NFL analysts have you covered at the 11th hour. Don't miss our last-minute prep for a loaded slate.
First, analytics writer Seth Walder breaks down three stat trends that could be pivotal this weekend. Then fantasy football writer Eric Moody runs through five players who are rostered in under 50% of ESPN fantasy football leagues as of Saturday and could be started in a jam. That's followed by NFL analyst Ben Solak predicting three potentially big surprises and NFL analyst Matt Bowen picking one key matchup to watch. Finally, sports betting analyst Pamela Maldonado gives her favorite bet of Week 2.
