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ESPN.com · Sep 6, 2025

NFL Week 1 predictions, fantasy sleepers, upset picks

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Week 1 of the 2025 NFL season is already underway, with the Eagles beating the Cowboys in the opener and the Chargers defeating the Chiefs in Brazil. We've been preparing for the regular season for weeks with previews and rankings, but just in case you still need some last-minute intel for the 14 games remaining on Sunday and Monday, our NFL analysts have you covered at the eleventh hour.

Full story at ESPN.com

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