Indianapolis Colts quarterback Jacoby Brissett came out of Sunday's game against the Pittsburgh Steelers after suffering a leg injury in the second quarter and never returned.
According to Stephen Holder of The Athletic, it's "likely" a knee sprain related"to the MCL.
The injury occurred when a Colts offensive lineman landed on Brissett while the quarterback was attempting a pass.
Veteran Brian Hoyer replaced the starter on the field and threw three touchdown passes in the eventual 26-24 loss to the Steelers.
The 34-year-old was signed just before the start of the season to help provide depth once Andrew Luck surprisingly retired and has now thrown passes for seven different NFL teams.