San Francisco 49ers star wide receiver Deebo Samuel will miss Sunday's game against the NFC West rival Los Angeles Rams due to a hamstring injury, according to ESPN's Adam Schefter.
Samuel is coming off a career year in 2021. He caught 77 passes for 1,405 yards and six touchdowns, and he carried the ball 59 times for 365 yards and eight scores. He earned All-Pro and Pro Bowl honors for the first time.
He has remained productive in seven games this season, making 32 grabs for 387 yards and two touchdowns, while also rushing for 138 yards and one score on 24 carries.