Newcastle United begin their 2021-22 Premier League campaign with a home match against West Ham.
A visit to Aston Villa follows with Manchester United away also on the early season agenda on September 11.
The Toon face a demanding run-in with Liverpool, Man City and Arsenal among their fixtures.
Read the full list below:
14/08/2021 15:00 Newcastle United v West Ham United
21/08/2021 15:00 Aston Villa v Newcastle United
28/08/2021 15:00 Newcastle United v Southampton
11/09/2021 15:00 Manchester United v Newcastle United
18/09/2021 15:00 Newcastle United v Leeds United
25/09/2021 15:00 Watford v Newcastle United
02/10/2021 15:00 Wolverhampton v Newcastle United
16/10/2021 15:00 Newcastle United v Tottenham Hotspur
23/10/2021 15:00 Crystal Palace v Newcastle United
30/10/2021 15:00 Newcastle United v Chelsea
06/11/2021 15:00 Brighton v Newcastle United
20/11/2021 15:00 Newcastle United v Brentford
27/11/2021 15:00 Arsenal v Newcastle United
01/12/2021 19:45 Newcastle United v Norwich City
04/12/2021 15:00 Newcastle United v Burnley
11/12/2021 15:00 Leicester City v Newcastle United
15/12/2021 20:00 Liverpool v Newcastle United
18/12/2021 15:00 Newcastle United v Manchester City
26/12/2021 15:00 Newcastle United v Manchester United
28/12/2021 15:00 Everton v Newcastle United
01/01/2022 15:00 Southampton v Newcastle United
15/01/2022 15:00 Newcastle United v Watford
22/01/2022 15:00 Leeds United v Newcastle United
09/02/2022 19:45 Newcastle United v Everton
12/02/2022 15:00 Newcastle United v Aston Villa
19/02/2022 15:00 West Ham United v Newcastle United
26/02/2022 15:00 Brentford v Newcastle United
05/03/2022 15:00 Newcastle United v Brighton
12/03/2022 15:00 Chelsea v Newcastle United
19/03/2022 15:00 Newcastle United v Crystal Palace
02/04/2022 15:00 Tottenham Hotspur v Newcastle United
09/04/2022 15:00 Newcastle United v Wolverhampton
16/04/2022 15:00 Newcastle United v Leicester City
23/04/2022 15:00 Norwich City v Newcastle United
30/04/2022 15:00 Newcastle United v Liverpool
07/05/2022 15:00 Manchester City v Newcastle United
15/05/2022 15:00 Newcastle United v Arsenal
22/05/2022 16:00 Burnley v Newcastle United
All fixtures are subject to change once live TV schedule has been finalised.