Manchester City boss Pep Guardiola made seven changes for the win at Arsenal and is set to recall key players such as Raheem Sterling and Ederson.
Defender Eric Garcia is again expected to miss out through injury.
Newcastle remain without winger Allan Saint-Maximin and captain Jamaal Lascelles as both continue to suffer the after-effects of Covid-19.
The Magpies will monitor Federico Fernandez, who missed the midweek defeat at Brentford through fatigue.
MATCH FACTS
Head-to-head
- Manchester City have won their past 11 Premier League home games against Newcastle United, a club record run against any top-flight opponent.