On April 15, 1969, the expansion San Diego Padres played the Los Angeles Dodgers for the first time. Claude Osteen pitched a three-hit shutout, Andy Kosco hit a grand slam off Johnny Podres, and the Dodgers won 14-0. They won the next night as well, 9-1 -- another complete game, another Kosco home run. The Dodgers won the first four times they played and nine of the first 11.
The Padres have never led the all-time series, which the Dodgers currently lead 485 to 404. The last time the Padres won the season series was in 2010.