Below are the quarterfinal matchups in League Series 1. Be sure to watch when games begin at 3 pm ET on the official MLS Twitch and Twitter pages, as well as MLSsoccer.com and the free MLS app.
- Match 1: KingCJ0 (D.C. United) vs. PhilB94_ (Toronto FC)
- Match 2: xbleu7 (Austin FC) vs. Alekzandur (Sporting Kansas City)
- Match 3: GAdamou10 (New York Red Bulls) vs. Skills_Shack (Vancouver Whitecaps FC)
- Match 4: cisseSZN (Philadelphia Union) vs. didychrislito (NYCFC)