The Mets lost the rubber game for the second consecutive series as the Marlins won 7-3 in Miami.
Bartolo Colon lost for the first time this season after four consecutive wins. He gave up four runs and nine hits with one strikeout in 6 2/3 innings.
Ichiro Suzuki, 41, hit a three-run homer in the eighth off Alex Torres to put it away for the Marlins. Giancarlo Stanton (three RBI) hit a two-run homer in the first.
Michael Cuddyer hit a two-run homer in the first for the Mets.