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NFL Week 6 picks: Browns deal Cards first loss; Rams cover big number at Giants

Rondale Moore of the Arizona Cardinals dives for the end zone against the San Francisco 49ers at State Farm Stadium on October 10, 2021 in Glendale, Arizona. Credit: Getty Images/Christian Petersen

The NFL is the Usain Bolt of professional sports: Blink and you might miss it. Every year, the season goes by so fast. Week 6 brings with it the first slate of byes (Jets, Falcons, 49ers, Saints), which is good because it gives us two fewer chances to get things wrong.

Underdogs went 6-9-1 against the spread (ATS) last week, their first losing campaign of the season.