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NFL Week 3 picks: Giants beat 49ers, Baltimore tops KC on MNF; Colts crush Jets; Falcons lock of the week

Giants quarterback Daniel Jones throws before an NFL game against the Bears in Chicago on Sunday. Credit: AP/Charles Rex Arbogast

The NFL season goes by fast. Really fast. Starting 0-2 is not ideal. Starting 0-3 is a nearly impossible hole to dig out of, so the theme of Week 3 will be desperation for the 11 teams that lost their first two games.

Favorites went 7-8 against the spread (ATS) last week (one game was a pick ‘em) after going 8-7-1 in Week 1. Home teams went 11-5 straight up and 8-8 ATS, bringing their records to 19-13 and 17-14-1.