An MRI revealed New York Giants star running back Saquon Barkley suffered a high ankle sprain that could sideline him anywhere from four to eight weeks, a source told ESPN's Adam Schefter.
The longer timeline is considered more likely, the source said.
The Giants have a bye in Week 11, which could give him eight weeks to recover and allow him to return for the last six games.
Barkley suffered the injury to his right ankle in the second quarter of the Giants' 32-31 victory over the Tampa Bay Buccaneers on Sunday.