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ESPN.com · Sep 5, 2025

NFL Week 1 picks, predictions, schedule, odds, fantasy tips

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The Week 1 NFL schedule for the 2025 season brings some exciting matchups. The Chiefs will face the Chargers in Brazil, the Lions take a trip to Lambeau Field and a must-see QB duel between Lamar Jackson and Josh Allen will be held in Buffalo.

Full story at ESPN.com

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