It’s difficult to call a Week 3 matchup a must-win game for a team that’s not expecting to make the playoffs. But if the (0-2) New York Giants are going to play meaningful games late in the season, they need to find a way to defeat the injury-ravaged (1-1) San Francisco 49ers on Sunday.
As much as the Giants are dealing with key injuries to Saquon Barkley and Sterling Shepard, that pales in comparison to the 49ers who will be without several key starters on Sunday including quarterback Jimmy Garoppolo, and running backs Raheem Mostert and Tevin Coleman.