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Giants vs. 49ers: Prediction, Betting Picks, and Expert Analysis as New York Injuries Begin to Pile Up

Home | NYC Teams | New York Giants | Giants vs. 49ers: Prediction, Betting Picks, and Expert Analysis as New York Injuries Begin to Pile Up

Raymond Carlin III-Imagn Images

The New York Giants face a crucial test when they host the San Francisco 49ers at MetLife Stadium on Sunday at 1 p.m. With a 2-6 record and the season quickly slipping away, this NFC matchup pits two teams heading in opposite directions.

The Giants’ offense, averaging 21.4 points per game and now without Cam Skattebo, will need to overcome their persistent red zone struggles against a disciplined 49ers defense.