No matter what happens in the first 14 games of the 2018 season, Giants quarterback Eli Manning can do something he never has done before in Week 16: Beat the Colts.
The Colts are one of two teams in the NFL that Manning has not defeated during his 14-year Hall of Fame career. Which is the other team that always has his number?
Which team does he have the most wins against? The most touchdown passes? The most yards?
Which team has never intercepted him?
With an assist from ProFootballReference.