The NFL has released the new schedules for every team, and have the New Orleans Saints opening the 2018 season at home in the Mercedes-Benz Superdome. They’ll immediately begin their NFC South title defense against the Tampa Bay Buccaneers.
Complete 2018 Regular Season Schedule
| Week | Opponent | Date/Time (CT) | Network |
| 1 | vs Tampa Bay | 9/9 noon | FOX |
| 2 | vs Browns | 9/18, noon | FOX |
| 3 | @ Atlanta | 9/23, noon | FPX |
| 4 | @ Giants | 9/30, 3:25 p. |