Good luck to the San Francisco 49ers: when they kick off with the New Orleans Saints on Sunday, they’ll be doing so without any of the major players from last year’s 48-46 win at the Superdome.
Quarterback Jimmy Garoppolo, tight end George Kittle, and running back Raheem Mostert were all preemptively ruled out. The final injury report added leading receiver Deebo Samuel and backup running back Tevin Coleman to the list. On top of all that, the best 49ers player in last season’s game, Emmanuel Sanders, switched sides in the offseason and is now playing for New Orleans.