The Saints can extend their three-game winning streak and imrpove on their 4-4 record to move above .500 for the first time since they ended 2013 with an 11-5 record. The Titans hold a six-game losing streak and will play their first game under interim coach Mike Mularky, and their first game with quarterback Marcus Mariota back after he missed the last two with an MCL knee sprain.

Brees threw for 337 yards and Marques Colston caught two fourth-quarter touchdowns for the Saints to win 22-17 in Nashville. The Titans' first-round drafted rookie quarterback that day was Jake Locker.