(+3.5) and the Denver Broncos (-3.5) (-3.5). The game is in Denver, giving the Broncos home field advantage and the elevation figures to be a factor as well.
The Colts come into come in at 1-2-1 and need a win. They will be without their All-Pro running back Jonathan Taylor as he nurses an ankle injury. This means quarterback Matt Ryan will be asked to throw the ball a lot against a solid Broncos secondary.
If Indianapolis wants to win this game, its defense needs to have a great game. Pressuring the quarterback and forcing turnovers will be key for the Colts.