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Patriots vs. Bills injury report: Damien Harris, Isaiah Wynn won't play Week 13

The New England Patriots will be a little shorthanded on offense for Thursday night's Week 13 matchup against the Buffalo Bills at Gillette Stadium.

The Patriots ruled out running back Damien Harris (thigh) and offensive tackle Isaiah Wynn (foot) on their injury report after Wednesday's practice.

Harris' absence puts more of a burden on second-year running back Rhamondre Stevenson, who leads the Patriots in rushing yards (680) and rushing touchdowns (four). Yodny Cajuste is the most likely starting right tackle in place of Wynn, although he's listed as questionable with a calf injury.