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NFL odds Week 7: Opening spread, moneyline for Patriots vs. 49ers game

The New England Patriots find themselves in the unfamiliar position of third place in the AFC East entering their Week 7 matchup against the San Francisco 49ers at Gillette Stadium.

The Patriots are under .500 in October for the first time since 2002, and they'll need to show plenty of improvement offensively to score on a 49ers defense that ranks No. 5 in yards allowed per game and 10th in points allowed per game.

New England failed to score a single touchdown in its 18-12 loss to the Denver Broncos in Week 6. Patriots quarterback Cam Newton threw two interceptions and his wide receivers failed to consistently get open.