The Patriots ruled out Tarell Brown after he missed back-to-back practices to close out the week.
Dont'a Hightower, Dion Lewis and Trey Flowers are all questionable after they were limited in another practice.
Colts quarterback Andrew Luck is also questionable after being a limited participant Wednesday and Thursday and a full participant today.
Here is the Patriots' full injury report.
Out:
CB Tarell Brown (foot)
Limited:
DE Trey Flowers (shoulder, knee)
LB Dont'a Hightower (ribs)
RB Dion Lewis (abdomen)