Sit and start is relative and league dependent, so consider some of these suggestions more “fliers” and “fades” (note that some are targeted for DFS).
Good luck with your Week 16 lineups.
Houston Texans @ Tampa Bay Buccaneers
Start: Will Fuller, Breshad Perriman
Fuller is always at risk of leaving with a hamstring injury, but he’s also got the upside to finish as the No. 1 fantasy wide receiver any given week and especially this week when he’ll face a Buccaneers defense that ranks first against the run in DVOA but has allowed the most fantasy points to wideouts this season.