Expectations are high for the Purdue Boilermakers going into the season, ranked No. 1 in the preseason Associated Press poll for the first time, and bookmakers are giving them the added pressure of being preseason national championship favorites.
Purdue is the consensus favorite to win the national championship ahead of the 2025-26 men's college basketball season, showing +850 odds at ESPN BET. Last season's runners-up, the Houston Cougars, are the consensus second-favorites at +1000 at ESPN BET, with Duke (+1100), UConn (+1200) and Kentucky (+1500) rounding out the top five.