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College Football Odds Week 4: Picks Against the Spread for Updated Top 25 Games

It's taken a few weeks for the 2020 college football season to get rolling, but the action in Week 4 will more closely resemble what fans expect from a Saturday in the fall. While ACC and Big 12 teams continue their seasons, the SEC campaign will begin Saturday.

All 14 teams from the SEC will be playing, which includes a trio ranked in the top five of the AP Top 25 poll—No. 2 Alabama (at Missouri), No. 4 Georgia (at Arkansas) and No. 5 Florida (at Ole Miss). The national champion, No. 6 LSU, will also be making its season debut, hosting Mississippi State.