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College Football Betting Odds Week 1: Picks Against the Spread for Top Games

College football makes its triumphant return on Labor Day weekend with a shortened schedule before the majority of teams make their debut in Week 2.

The COVID-19 pandemic has severely altered the original Week 1 schedule. The FCS got started with Austin Peay vs. Central Arkansas last weekend, and the Group of 5 will now take center stage, with American Athletic Conference and Conference USA teams starting their campaigns for a New Year's Six bowl invite.

No Top 25 team is scheduled to play this weekend. But with the Big 10 and Pac-12 seasons still up in the air and delayed, there are opportunities for some of the teams playing this weekend to get in on the rankings fairly early this season.