UFC 322 Odds: Jack Della Maddalena vs. Islam Makhachev

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Jack Della Maddalena is in a familiar position heading into UFC 322. | Getty/UFCTreading into familiar territory, Jack Della Maddalena has opened as an underdog for his first title defense.

Maddalena will look to defend his welterweight title for the first time against Islam Makhachev in the main event at UFC 322 on Nov. 15 at Madison Square Garden in New York. The champ has opened as a sizeable +205 underdog against the challenger, a -265 favorite.

Aussie Champ Accustomed to Underdog Role

However, Maddalena is no stranger to upsetting the odds. The Australian was a heavy underdog going into his title win over Belal Muhammad at UFC 315 this past May. While Maddalena had also opened as an…