The vacant UFC strawweight title will be decided when Virna Jandiroba faces Mackenzie Dern in the co-main event of UFC 321 on October 25, 2025, at the Etihad Arena in Abu Dhabi. This matchup carries significant stakes as Zhang Weili has vacated her strawweight championship to pursue the flyweight title against Valentina Shevchenko at UFC 322.
With Zhang Weili’s decision to move up in weight, the strawweight division finds itself in transition. Both fighters represent the future of the 115-pound division, with Jandiroba currently ranked first in the standings and Dern positioned at fifth.