The original main event for UFC Fight Night 68 was a pivotal light heavyweight bout between the Louisiana native Daniel Cormier and Ryan Bader, but Cormier was removed from the card to take on Anthony Johnson for the vacant UFC Light Heavyweight Championship at UFC 187, which he won. The new main event was a 5-round middleweight bout between MMA legend Dan Henderson and the #13 ranked middleweight Tim Boetsch.
Just like at every UFC event, UFC Fight Night 68 saw many fighters take a step forward in their career, whereas others were not as successful and had to take a step back in their career.