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New York Yankees vs. Chicago White Sox Odds, Analysis, MLB Betting Pick

Two teams heading in opposite directions will clash in the Windy City on Monday when the slumping New York Yankees (68-42) visit the surging Chicago White Sox (41-70) as large road favorites at the sportsbooks.

The White Sox return home following a three-game road sweep of the Tampa Bay Rays, and they bring a four-game winning streak overall into this matchup with the Yankees.

MLB betting line: The Yankees opened as -222 favorites (wager $222 to win $100); the total is at 9.5 runs, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)

MLB betting pick, via OddsShark computer: 4.