Here are the matchups heading into Missouri high school football district semifinals. All games are listed by MSHSAA for Friday at 7 p.m. — unless otherwise noted.
Class 1
District 1
- Caruthersville @ Thayer
- Hayti @ St. Vincent
District 2
- Paris with Faith Walk@ South Callaway
- Louisiana @ Mark Twain
District 3
- Cole Camp @ Skyline
- Tipton @ Windsor
District 4
- Pierce City @ Marionville
- Cabool @ Lockwood
District 5
- Crest Ridge @ Adrian
- University Academy @ Sweet Springs
District 6
- Fayette @ Marceline
- Harrisburg @ Westran
District 7
- Penney @ South Harrison
- Princeton @ Milan
District 8
- Polo @ Mid-Buchanan
- West Platte @ East Buchanan
District 2
District 1
- Central (New Madrid County) @ East Prarie
- Jefferson (Festus) @ Kelly
District 2
- Cuba @ Lutheran St.