Here are the matchups for the 2020 high school football district championships in Missouri. All games are listed by MSHSAA, as of Saturday evening, for Friday at 7 p.m. unless otherwise noted.
Class 1
- Hayti @ Thayer
- Mark Twain @ South Callaway
- Windsor @ Skyline
- Lockwood @ Marionville
- Sweet Springs @ Adrian
- Harrisburg @ Marceline
- Penney @ Princeton with Mercer
- East Buchanan @ Mid-Buchanan
Class 2
- Central (New Madrid) @ Jefferson (Festus)
- Duchesne @ Lutheran St. Charles
- Mountain-View Liberty @ Fair Grove
- Sarcoxie @ Lamar
- North Callaway @ Hallsville
- Monroe City @ Palmyra
- Warsaw @ Butler
- Lafayette County @ St.