Missouri made some nice cash the last couple of seasons, going 20-8 against the spread, but betting trends are born to reverse themselves eventually, and the offensively challenged Tigers are just 2-6 ATS this season. Missouri also rides a dismal three-game losing streak into a home date with Mississippi State Thursday night in Columbia.
Point spread: Bulldogs opened as 7.5-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 35.0-23.8 Bulldogs
Why the Mississippi State Bulldogs can cover the spread
MSU won its third game in a row two weeks ago, beating Kentucky 42-16, covering as a two-touchdown home favorite.