Bieber labored through the worst start of his young career on Tuesday, allowing seven runs in 1 2/3 innings in a loss to the Pirates. The rookie is 2-0 with a 4.58 ERA in three road starts this season.
Santana made his first start of the season after finger surgery in February, allowing three runs in five innings against the Blue Jays on Wednesday. His command was fine, but his average fastball velocity was down to 90 mph.