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College football picks, Week 6

Matt Charboneau, Angelique S. Chengelis, John Niyo and Bob Wojnowski of The Detroit News offer their predictions for top games in Week 6 of the college football season. All picks are made against the spread.

Michigan -22 at Indiana

Charboneau: Michigan

Chengelis: Michigan

Niyo: Michigan (best bet)

Wojnowski: Michigan

Ohio St. -25.5 at MSU

Charboneau: Ohio St. (best bet)

Chengelis: Ohio St.

Niyo: Ohio St.

Wojnowski: Ohio St. (best bet)

Ball St.