If the Miami Dolphins believe that Ryan Fitzpatrick gives them the best chance to win, then it is clear that someone is doing drugs. If they think that Fitzpatrick gives them the best chance to lose, then starting him makes sense.
Maybe Brian Flores is playing the odds here. Fitzpatrick has a history of throwing more than one pick-six in a game and he has also had a tendency to throw four touchdowns a game. He is wildly inconsistent but maybe Flores thinks that he is due for one of the latter type games.
Starting Fitzpatrick at this point makes no sense.