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Dolphins, NFL's No. 1 scoring defense, goes up against Kyler Murray, Cardinals

4:25 p.m. ET | CBS

Matchup rating: 54.9 | Spread: ARI -4.5 (48)

What to watch for: Despite the Cardinals playing well as of late, they'll be down Byron Murphy Jr., and maybe Dre Kirkpatrick, at cornerback. If Kirkpatrick is out too, watch for Miami rookie QB Tua Tagovailoa to have a big outing, because whomever Arizona cornerback Patrick Peterson isn't guarding will be picked on all day. -- Josh Weinfuss

Bold prediction: The Dolphins will hold Cardinals wideout DeAndre Hopkins to under 50 receiving yards.