face the Arizona Cardinals (+10). The NFC West matchup could go a long way to determining how the NFC playoff picture plays out the rest of the way through the 2022 season. The 49ers come into tonight’s game at 5-4, a half-game behind the division leading Seattle Seahawks (-3.5). The Cardinals are 4-6 on the season, two games behind Seattle and 1.5 games behind the 49ers.
In the current NFC playoff picture, the 49ers are sitting in the seventh-and-final spot while Arizona is on the outside looking in as the 11th placed team.