Troy Williams scored 23 points and JaMychal Green added 21 and eight rebounds as Memphis finished double-overtime on an 11-2 run to defeat the Rockets, 134-125.
Montrezl Harrell scored a team-high 20 points and 10 rebounds. James Harden finished with 14 points, 10 rebounds and nine assists.
JaMychal Green drilled a right corner three to give the Grizzlies at 13-point advantage and the team's largest lead of the night, 21-8 with 5:01 left in the first quarter.
Memphis shot 41.3% from the field and 17-44 (38.