Our first fixture after a fortnight off will always be highly anticipated, but this is a particularly big date as Manchester City are the opponents, in the first derby of the campaign.
The Etihad Stadium will play host to the Reds and the Blues at 16:30 BST but, before all that, both managers are set to appear before the media to preview the contest.
You can watch Ruben Amorim’s press conference in full on MUTV in the United App and on ManUtd.com from 13:30 BST on Friday.
We’ll have all the breaking news stories and clips from the Reds’ head coach, plus loads more exclusive content as the build-up to the 197th Manchester derby heats up.